Vitiligo, a family business

There comes a time in the life of every vitiligo patient when we ask ourselves: „Will my children develop vitiligo ?”
The frequency of vitiligo among siblings is 6.1% which is about 18 times higher then the usual population frequency, suggesting a major genetic component in the disease. The probability that a pair of twins will both have vitiligo is 23% indicating that a non-genetic component also plays a role. 

According to a study published in the Pigment Cell Research magazine, vitiligo occurs with a frequency of 0.1 to 2.0% in various populations. The study surveyed a number of 2642 subjects from North America and UK regarding the disease characteristics and familial background. More then 83% of subjects were Caucasian with equal distribution of the disease in both males and females.

Subjects with an earlier disease onset were more prone to have relatives with vitiligo. Also, vitiligo patients and their first degree relatives were found to have an elevated frequency of some other autoimmune diseases: vitiligo itself, autoimmune thyroid disease (particularly hypothyroidism), pernicious anemia, Addison's disease, systemic lupus erythematosus. This associations reveal that vitiligo shares the same genetic background as these other autoimmune disorders.

Source:
Pigment Cell Research. 16(3):208-214, June 2003.
Alkhateeb, Asem 1; Fain, Pamela R. 1,2,3; Thody, Anthony 4; Bennett, Dorothy C. 5; Spritz, Richard A. 1,2

category: 
News

Comments

Submitted by Coach Outlet (not verified) on

Great site! Thanks for being here and sharing this awesome stuff <a href="http://www.coachhandbagoutletonline.com/" title="Coach Outlet">Coach Outlet</a>.I was reading through some of your blog posts on this website and I believe this web site is very informative <a href="http://www.coachhandbagoutletonline.com/" title="Coach Outlet Online">Coach Outlet Online</a> ! Keep on posting.You’re the best, thanks for the awesome article. I’m having troubles <a href="http://www.coachhandbagoutletonline.com/" title="Coach Outlet Store">Coach Outlet Store</a> subscribing to your blogs feed <a href="http://www.coachhandbagoutletonline.com/" title="Coach Outlet Online Store">Coach Outlet Online Store</a>. Thought I’d let you know <a href="http://www.coachhandbagoutletonline.com/" title="Coach Factory Outlet Online">Coach Factory Outlet Online</a>.

Submitted by Christian louboutin (not verified) on

Once you’ve selected your colours, the ateliers at Louis Vuitton then use unique software

to design your one-of-a-kind hand luggage before scurrying off to assemble your

bespoke bag by hand.
<a href=http://www.paschersacvuitton.org/>Louis Vuitton pas cher</a>
<a href=http://www.handtaschenonline4shop.com/>Louis Vuitton Online shop</a>
<a href=http://www.louisvuittontas.biz/>louis vuitton</a>
<a href=http://www.louis-vuittonpascher.org/>Louis Vuitton</a>
<a href=http://www.louisvuitton-rabatt.biz/>Louis Vuitton Online shop</a>
<a href=http://www.christianlouboutinsoldes.biz/>Christian louboutin</a>
They take eight weeks to be delivered.

Submitted by coach outlet (not verified) on

One thing <a href="http://www.coachs-factory-outlet.org/"><strong>Coach Factory Outlet</strong></a> that you should immediately get to know that the fashion trend is the coach handbags. <a href="http://www.coachoutletonline2you.us/"><strong>Coach Outlet</strong></a> is a leather brand which well-known and very popular in the United States. <a href="http://www.hotcoachoutletsale.net/"><strong>Coach Outlet</strong></a> selling points are high quality and aesthetic design from <a href="http://www.mylovecoachoutletonline.org/"><strong>Coach Outlet Online</strong></a>. <a href="http://www.coachoutlettousa.net/"><strong>Coach Outlet</strong></a> has been leading the fashion footsteps, as the inventor of the popular fashion trends <a href="http://www.coachfactoryoutlet4you.com/"><strong>Coach Factory</strong></a>. All <a href="http://www.coachs-factory-outlet.org/coach-hobo-bags-c-4.html"><strong>C... Hobo Bags</strong></a> are attractive in any situation and <a href="http://www.coachoutletonlinetousa.org/"><strong>Coach Outlet Online</strong></a> can make you very attractive. If you have been looking for the fashion trend about <a href="http://www.louisvuittonfrances.com/"><strong>Sac Louis Vuitton</strong></a>, then the <a href="http://www.coachs-factory-outlet.org/"><strong>Coach Factory</strong></a> can tell you what is the fashion. <a href="http://www.coachoutletonline2you.us/"><strong>Coach Outlet Online</strong></a>. currently has produced a variety of fashion products in the world <a href="http://www.hotcoachoutletsale.net/"><strong>Coach Outlet Online</strong></a>. And <a href="http://www.mylovecoachoutletonline.org/"><strong>Coach Outlet</strong></a> can be your first choice, which would make you so fashion and thrilled. . The h<a href="http://www.coachoutlettousa.net/"><strong>Coach Outlet Online</strong></a> is very profitable and many females look for the purses as wholesale Coach Purses that they love and enjoy so much. <a href="http://www.coachfactoryoutlet4you.com/"><strong>Coach Factory Online</strong></a> can be very excitingly searching on the <a href="http://www.coachoutletonlinetousa.org/"><strong>Coach Outlet</strong></a> and finding out what appears to be a special bag at a marvelous price from <a href="http://www.coachs-factory-outlet.org/"><strong>http://www.coachs-factory.... Search for a Coach Handbag at <a href="http://www.louisvuittonfrances.com/"><strong>Louis Vuitton pas cher</strong></a> right now! Welcome!

Submitted by Cheap Oakleys (not verified) on

<a href="http://www.cheap-oakleysunglassesonline.com/">Cheap Oakley Sunglasses</a> feature Iridium-coated lenses to lessen the sun's glare and provide contrast. Oakley owners must exercise care when handling their sunglasses to avoid scratching the delicate the Iridium coating, which is registered to <a href="http://www.cheap-oakleysunglassesonline.com/">Cheap Oakleys</a>. However, if you scratch your the lenses, you can remove scratches safely without causing further damage. Avoid using cleaning solution with <a href="http://www.cheap-oakleysunglassesonline.com/">Oakley Sunglasses Online</a> to prevent warping the Iridium coating and making the problem worse. Repair scratches on your Oakley lenses to avoid lens replacement.

Submitted by monsterbeats (not verified) on

Distinctive <a href="http://www.palesz.info/">mulberry outlet</a> resources match

<a href="http://www.beatsmonstermall.com/">monster beats by dre</a>a variety of
<a href="http://www.windows-7-key.com/">Windows 7 Ultimate Key</a>colors.Moreover,

it is easy to even get your brown mulberry bag customized to
<a href="http://www.beatsmonstermall.com/">monster dre beats</a>your individual
<a href="http://www.beatsmonstermall.com/">monster beats</a>specifications and

you'll find an excellent many different types of resources to choose from for
<a href="http://www.windows-7-key.com/">windows 7 key</a>pick. For all time,

significant importance may be put about the layout and craftsmanship of Mulberry

<a href="http://www.windows-7-key.com/">Windows 7 Professional Key</a>handbag. The

understated design and style and beautiful handicraft have much to try and do with

sophisticated Anglo-British
<a href="http://www.beatsmonstermall.com/">solo beats</a>living and great
<a href="http://www.beatsmonstermall.com/">beats by dre sale</a>breeding. Mulberry

handbag is regarded as understated but also edgy and classy.
<a href="http://www.windows-7-key.com/">Windows 7 Home Premium Key</a>Numerous

supplies match unique colors. Furthermore, you're able to
<a href="http://www.beatsmonstermall.com/">monster beats</a> even get your brown

mulberry bag custom-made in your private specifications and
<a href="http://www.beatsmonstermall.com/">dre monster beats</a>you will discover

a fantastic a variety of variations of substances out there for choice. For all

time, sizeable significance has been put over the pattern and craftsmanship of
<a href="http://www.beatsmonstermall.com/">dr dre beats</a>Mulberry handbag. The

understated pattern and beautiful handicraft have a lot of to accomplish with
<a href="http://www.palesz.info/">mulberry outlet uk</a>tasteful Anglo-British
<a href="http://www.windows-7-key.com/">windows 7 product key</a>living and

advantageous breeding. Mulberry handbag is regarded as understated but
<a href="http://www.beatsmonstermall.com/">solo hd beats</a>also edgy
<a href="http://www.palesz.info/">discount mulberry</a> and classy.

Submitted by Sac Louis Vuitton (not verified) on

Once you’ve selected your colours, the ateliers at Louis Vuitton then use unique software to design your one-of-a-kind hand luggage before scurrying off to assemble your bespoke bag by hand.
<a href=http://www.paschersacvuitton.org/>Sac Louis Vuitton</a>
<a href=http://www.louisoutletshop.com/>louis vuitton taschen</a>
<a href=http://www.louisvuittontas.biz/>louis vuitton</a>
<a href=http://www.louis-vuittonpascher.org/>Louis Vuitton</a>
<a href=http://www.louisvuitton-rabatt.biz/>Louis Vuitton Online shop</a>
<a href=http://www.christianlouboutinsoldes.biz/>Christian louboutin</a>
They take eight weeks to be delivered.

Submitted by christian loubo... (not verified) on

The trend of the <a href="http://www.cheap-louboutin-outlet.net/" title="christian louboutin pumps"><b>christian louboutin pumps</b></a> also change based on seasons. There are so many different types of <a href="http://www.cheap-louboutin-outlet.net/christian-louboutin-wedges-c-2.html" title="Christian Louboutin Wedges"><b>Christian Louboutin Wedges</b></a> high heel shoes and sometimes we are confused about which should we choose.

Add new comment

CAPTCHA
This protects against automated submits.
Image CAPTCHA
Enter the characters shown in the image.